1st International Course on
Integrated Biomarkers

Biochemical and Bioimaging Endpoints in Cardiocerebrovascular Diagnosis,
Prevention, Therapy and Drug Development


Biomarkers 2005

To facilitate the dialogue among the multidisciplinary scientists, definition of the acronyms and of more specialized terms have been reported. Every amendment is welcome.

Andrea P. Peracino
Stefano Bellosta
Nicola Ferri
Riccardo Roggeri

Method validation should be performed before a test procedure is placed into routine use. Validation may be accomplished by thoroughly testing reference materials or by comparison of results of tests performed by an alternative method. For each method, the diagnostic department should verify the manufacturer’s claims and any adjustments before initiating patient evaluation. Method validation should provide evidence of: accuracy, imprecision, sensitivity, specificity, linear reportable range , linearity, referemce material. Validation in Biochmistry, Validation in Imaging


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