Biochemical
and Bioimaging Endpoints in Cardiocerebrovascular Diagnosis,
Prevention, Therapy and Drug Development
GLOSSARY
To
facilitate the dialogue among the multidisciplinary scientists,
definition of the acronyms and of more specialized terms have been
reported.
Every amendment is welcome.
By: Andrea P. Peracino
Stefano Bellosta
Nicola Ferri
Riccardo Roggeri
The result of the performance (or nonperformance) of a function(s) or process(es). . Outcomes may be described as: immediate, intermediate or final, direct or indirect, intended or unintended. Outcomes in a logic model typically have an action word associated with them (eg, increased or improved) and represent the consequences of the activities and outputs. When referring to CVD, this is a term given to mean significant events – such as heart attacks, strokes or sudden death – measured within long-term, major clinical studies.
an outcome measure that is used in place of a primary endpoint (outcome). Use of a surrogate endpoint assumes that it is a reliable predictor of the primary endpoint(s) of interest.
