1st International Course on
Integrated Biomarkers

Biochemical and Bioimaging Endpoints in Cardiocerebrovascular Diagnosis,
Prevention, Therapy and Drug Development

GLOSSARY

Biomarkers 2005



To facilitate the dialogue among the multidisciplinary scientists, definition of the acronyms and of more specialized terms have been reported. Every amendment is welcome.

By:
Andrea P. Peracino
Stefano Bellosta
Nicola Ferri
Riccardo Roggeri



Definition:
Description:
References:
Lp(a) consists of a particle of low-density lipoprotein cholesterol (LDL-C) linked by a disulfide bond to a large hepatically derived glycoprotein, apolipoprotein(a), which is structurally similar to plasminogen. In theory, then, Lp(a) could promote cardiovascular disease in two ways: its apolipoprotein(a) moiety could promote thrombogenesis and its LDL-C moiety could promote atherogenesis.


 


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